Magnesium sulphate injection 50% w/v
This leaflet is to help you get the most from your medicine.
Please read this leaflet carefully BEFORE you take your medicine. If you have any questions or you want to know more about this medicine, please ask the staff looking after you.
What is your medicine?
Your medicine is called Magnesium Sulphate Injection 50% w/v. It is a sterile solution for injection and contains 1g of magnesium sulphate (the active ingredient) in each 2ml of injection. It also contains sodium hydroxide, sulphuric acid and water for injections.
Magnesium Sulphate Injection 50% w/v is supplied in cartons of 1, 5 or 10 glass ampoules each containing 2ml of solution.
Magnesium Sulphate belongs to a group of medicines called mineral supplements.
Who makes it?
The Marketing Authorisation Holder is
It is made by
What is this medicine used for?
Magnesium Sulphate Injection 50% w/v is used to treat magnesium deficiency (lack of magnesium), where it is not possible for the medicine to be taken by mouth. This could be due to malabsorption, severe diarrhoea, chronic alcoholism, malnutrition or having to have all nutrients by injection.
Before using this medicine
Please tell your doctor if the answer to any of the following questions is “yes”.
- Are you suffering from any form of heart disease, for example, have you had a heart attack or heart block (where your heart beat signals are delayed)?
- Are you receiving drugs for heart disease called cardiac glycosides, e.g. digitoxin?
- Do you suffer from poor kidney function?
- Have you been prescribed any of the following medicines: opioids (e.g. morphine); barbiturates (e.g. amylobarbitone); or hypnotics (e.g. nitrazepam)?
- Are you going to have an anaesthetic where a muscle relaxant will be used?
- Are you pregnant, likely to be pregnant, or breast feeding?
- Are you taking any medicines containing nifedipine (a calcium channel blocker) for angina or high blood pressure?
If the answer to any of these questions is YES, tell your doctor before taking this medicine. They may want to change your treatment or give you special advice.
How will I be given Magnesium Sulphate Injection 50% w/v?
Magnesium sulphate is to be injected into a muscle or a vein, as directed by the doctor. For injection into a vein, the solution should be diluted to 20% or less, and the rate of injection should be less than 1.5ml per minute of a 10% solution. In children the solution should also be diluted to 20% if being injected into a muscle.
The doctor may want to perform regular blood or other tests to monitor your condition.
For mild magnesium deficiency: 1 gram every 6 hours for 4 doses injected into a muscle.
For severe magnesium deficiency: Up to 250 milligrams per kilogram of body weight injected into a muscle every 4 hours, or 5 grams per litre of solution is given intravenously as an infusion over 3 hours.
What if I take too much?
If you think you have been given too much of this medicine, tell your doctor immediately. Signs of too much magnesium include flushing, thirst, drowsiness, feeling sick or being sick, confusion, muscle weakness, loss of reflexes, slow and/or shallow breathing, low blood pressure and irregular heartbeat.
After using Magnesium Sulphate Injection 50% w/v
Side effects after Magnesium Sulphate Injection are usually a sign that your body has now got more than enough magnesium. Signs of too much magnesium include flushing, thirst, drowsiness, felling sick or being sick, confusion, muscle weakness, loss of reflexes, slow and/or shallow breathing, low blood pressure and irregular heartbeat.
If you think this medicine has upset you in any way please tell your doctor.
How to store this medicine
Magnesium Sulphate Injection 50% w/v must be stored below 25°C.
Do not use this medicine after the expiry date shown on the pack.
KEEP THIS AND ALL MEDICINES OUT OF THE REACH OF CHILDREN.
Further information
This leaflet does not contain all the information about your medicine. If you have any questions or are not sure about anything, ask your doctor (or pharmacist), who will have access to further information.
YOU MAY WANT TO READ THIS LEAFLET AGAIN. PLEASE DO NOT THROW IT AWAY UNTIL YOU HAVE FINISHED YOUR MEDICINE.
This leaflet only applies to Magnesium Sulphate Injection 50% w/v.
Date of preparation of leaflet: October 2005
P1060C
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